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When Sifrhippus, the earliest known horse, first appeared in the forests of North America more than 50 million years ago, it would not have been mistaken for a Clydesdale.
It weighed in at around 12 pounds--and it was destined to get much smaller over the ensuing millennia.
Sifrhippus lived during the Paleocene-Eocene Thermal Maximum (PETM), a 175,000-year interval of time some 56 million years ago in which average global temperatures rose by about 10 degrees ...
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From spaghetti-like sea anemones to blobby jellyfish to filigreed oak trees, each species in nature is characterized by a unique size and shape. But the evolutionary changes that produce the seemingly limitless diversity of shapes and sizes of organisms on Earth largely remains a mystery. Nevertheless, a better understanding of how cells grow and enable organisms to assume their characteristic sizes and shapes could shed light on diseases that involve cell growth, including cancer and ...
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New clues about how Earth's remote ecosystems have been influenced by the industrial revolution have been uncovered. Until now they were locked away, frozen in the ice of glaciers.
So say scientist Aron Stubbins of the Skidaway Institute of Oceanography and colleagues.
They published results of their study in the March, 2012, issue of the journal Nature Geoscience. It shows that everything flows downhill, eventually.
The research was funded by the ...
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As scientists warn that the Earth is on the brink of a period of mass extinctions, they are struggling to identify ecosystem responses to environmental change. But to truly understand these responses, more information is needed about how the Earth's staggering diversity of species originated.
Curiously, a vexing modeling mystery has stymied research on this topic: mathematical models have told us that complex ecosystems, such as jungles, deserts and coral reefs, in which species ...
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More Grapes, Less Wrath: Hybrid Antimicrobial Protein Protects Grapevines from Pathogen
LOS ALAMOS, NEW MEXICO, February 20, 2012—A team of researchers has found a way to ensure that your evening glass of wine will continue to be available, despite the potential attack of Xylella fastidiosa (Xf), a bacterium that causes Pierce’s Disease and poses a significant threat to the California wine industry’s valuable grapevines.
Researchers from Los Alamos National Laboratory (LANL), University of California at Davis (UCD), and the U.S. Department of Agriculture’s Agricultural Research Service have created specially engineered grapevines that produce a hybrid antimicrobial protein that can block Xf infection.
Their research is published in the current edition of Proceedings of the National Academy of Sciences, "An engineered innate immune defense protects grapevines from Pierce’s disease," by Abhaya M. Dandekar, et al. The article’s online tracking number is 2011-16027R in the PNAS Early Edition to be published the week of Feb. 20, 2012.
By helping the vine fight the microbe with specific proteins, the scientists envision vineyards requiring less reliance on chemicals as growers seek to fend off the bacterium and the glassy-winged sharpshooter (Homalodisca vitripennis) insect that carries it. As the insect feeds on various plants, it distributes the microbe widely.
The key to the project’s success is the fact that early in an Xf infection, molecules on the outer membrane of the microbe interact with cells of the grapevine. By interfering with that interaction between microbe and vine, scientists can help the vines block the disease and go on to produce a healthy crop of grapes.
"One thing got us started: with almost any pathogen, the major problem is drug resistance," said Goutam Gupta, the corresponding author of the PNAS paper. "We wanted the plant to clear itself of the pathogen before it is infected, much as the body’s immune system naturally recognizes a pathogen and takes action to defeat it."
To make the effective protein, researchers fused two genes: one that encodes a protein to cut a specific molecule on the outer membrane of Xf, and another that triggers the bursting of the Xf bacterium’s outer wall, called lysis.
The team inserted the hybrid gene into grapevines and observed the plants’ response to Xf infection. "The hybrid protein apparently creates pores in the membrane of the Gram-negative bacterium, Xf," said Gupta, thus allowing the plant to fight back the infection. Sap from the engineered plants successfully killed Xf in laboratory tests, and the whole plants did not exhibit symptoms of Pierce’s disease after exposure to the Xf bacterium.
The antimicrobial gene may also protect other economically important plants from Xf-related diseases, and a similar strategy may be effective against a broad range of pathogen-induced plant and human diseases, Gupta said. X. fastidiosa is implicated in oleander leaf scorch, phony peach disease, plum leave scald, almond leaf scorch, Pierce's disease in grapes, and citrus X disease in Brazil.
Work on this project has been funded by the California Department of Food & Agriculture, the US Department of Agriculture - Agricultural Research Service, the LANL Center for Biosecurity Science, and the LANL Material Design Institute.
Image caption: Expression of a hybrid protein blocks Pierce’s Disease in grapevine. The hybrid protein (shown at the bottom right) creates pores in the membrane of the Gram-negative bacterium, Xf, that causes PD. Transgenic grapevine expressing the hybrid protein shows little or no leaf scorching as PD symptom upon Xf infection (top left) whereas the non-transgenic without the hybrid protein shows severe leaf scorching (top right).
About Los Alamos National Laboratory (www.lanl.gov)
Los Alamos National Laboratory, a multidisciplinary research institution engaged in strategic science on behalf of national security, is operated by Los Alamos National Security, LLC, a team composed of Bechtel National, the University of California, The Babcock & Wilcox Company, and URS for the Department of Energy’s National Nuclear Security Administration.
Los Alamos enhances national security by ensuring the safety and reliability of the U.S. nuclear stockpile, developing technologies to reduce threats from weapons of mass destruction, and solving problems related to energy, environment, infrastructure, health, and global security concerns.
In this issue of 1663, the science and technology magazine from Los Alamos National Laboratory:
- A new discovery in particle physics? The evidence for sterile neutrinos
- Algal biofuels: recent successes and remaining challenges
- Building upon x-ray vision with charged-particle radiography
- Metabolism in the primordial soup
- … and more
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You are subscribed to News - All NSF News for National Science Foundation Update. This information has recently been updated, and is now available.

Domestic cats, wild bobcats and pumas that live in the same area share the same diseases.
And domestic cats may bring them into human homes, according to results of a study of what happens when big and small cats cross paths.
Initial results of the multi-year study are published today in the scientific journal PLoS One by a group of 14 authors.
The joint National Science Foundation (NSF) and National Institutes of Health (NIH) Ecology and Evolution of ...

Biologists who released lizards on tiny uninhabited islands in the Bahamas have uncovered a seldom-observed interaction between evolutionary processes.
Jason Kolbe, a biologist at the University of Rhode Island (URI)--along with colleagues at Duke University, Harvard University and the University of California, Davis--found that the lizards' genetic and morphological (form and structural) traits were determined by both natural selection and a phenomenon called the founder ...
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IBEX Probe Glimpses Interstellar Neighborhood
EMBARGOED until 1 p.m. EST on January 31, 2012
LOS ALAMOS, NEW MEXICO, January 31, 2012—Space scientists, including researchers from Los Alamos National Laboratory, today described the first detailed analyses of captured interstellar neutral atoms—raw material for the formation of new stars, planets and even human beings. The information was presented in Washington, D.C., at a press conference sponsored by the National Aeronautics and Space Administration (NASA).
Researchers at the conference presented data from the Interstellar Boundary Explorer (IBEX), which directly sampled material carried from outside our solar system across the galaxy by solar and stellar winds. Full details of the research comprise a six-paper special section in the February edition of Astrophysical Journal Supplements.
IBEX was launched in October 2008 and has maintained an elliptical orbit around Earth ever since. The space probe uses a pair of special cameras, one of which was developed to a large degree at Los Alamos National Laboratory, to sample neutral atoms reaching Earth’s surroundings from the edges of the solar system and its immediate neighborhood.
Earth is mostly shielded from direct bombardment by interstellar particles because the solar wind—a blast of charged particles emanating from the surface of the Sun—creates a protective bubble around us that deflects charged particles back into space. Without this bubble, called the heliosphere, Earth would be pummeled by cosmic radiation. IBEX provides the first global view of the outer boundary of this protective bubble.
IBEX also provides a direct sample of the surrounding neutral gas, which blows as an interstellar wind through the solar system.
“Interstellar particles are the raw stuff that form stars, planets, and even us,†said Eberhard Moebius, a University of New Hampshire professor and IBEX team member currently on sabbatical at Los Alamos. UNH developed key systems of IBEX’s second camera. “In the beginning there was only hydrogen and helium. These two elements formed the first stars. When those stars collapsed and died, they spewed their material, including new elements created through the process of nuclear fusion, out into space. We can tell a lot about the evolution of our universe and perhaps gain insight into other galaxies and planetary systems by analyzing these particles.â€
With the capacity to detect and analyze helium, hydrogen, neon, and oxygen, IBEX has been able to provide researchers with more information about our galactic neighborhood and raise some pressing questions about it. The IBEX research team has been able to characterize the ratio of oxygen to neon in Earth’s present location and compare it to other data. The IBEX observations suggest that the ratio of neon to oxygen in material emanating from outside our solar system is larger than the ratio from within our solar system and also the Milky Way—our home galaxy—as a whole.
The ratio difference may suggest that the Sun’s present location differs from its birthplace, or that a significant amount of oxygen might be bound up in grains of dust floating in interstellar space. Regardless of which hypothesis is correct, the IBEX mission findings are significant because this is the first time scientists have been able to gain direct quantitative measurements of the hydrogen, oxygen, and neon flow from outside our solar system, along with far more detailed observations of the interstellar helium flow.
Which leads to another interesting IBEX discovery:
The IBEX team has learned that the interstellar wind blows at about 52,000 miles per hour—about 7,000 miles an hour slower than previously measured.
IBEX takes advantage of a nature-provided “speedometer†for the interstellar wind by observing the degree of deflection of the gas on its journey into the solar system and past the Sun. The Sun’s gravity deflects slower atoms to a stronger degree than it deflects faster atoms. IBEX is able to measure the flow direction in Earth’s orbit with high precision, therefore providing the true speed and direction of the interstellar wind. With this tool, the researchers have been able to gain a better understanding of where Earth currently resides relative to known nearby clouds of interstellar material within our home planet’s galactic neighborhood.
These nearby interstellar clouds are denser than the surrounding space and are moving at substantial speeds. Astronomers have measured the speed of many neighboring clouds and wondered about Earth’s position among the closest clouds because the previously known interstellar wind speed did not match with any of the closest clouds. However, the new IBEX observations place the solar system within what is called the Local Interstellar Cloud.
Astronomers tell us that Earth is traveling near the edge of this cloud and will leave it at any time within the next few thousand years—just the blink of an eye on astronomical time scales. When this occurs, the heliosphere, the protective bubble surrounding us, may expand significantly since it will be less constrained by the sparsely populated region it enters. On its journey roughly in the direction of the center of the Milky Way, Earth and our solar system will meander toward and into the next cloud over, called the G cloud (named for the cloud toward the galactic center).
Just three and a half years into the IBEX mission, at a time when the two Voyager spacecraft are due to exit the heliosphere within the next decade, who knows what other surprises researchers will uncover about our solar system and its immediate neighborhood? Only time will tell.
“How wonderful it is to see that some of the same technologies developed at Los Alamos National Laboratory for keeping our nation safe are being used to understand how Earth keeps itself safe from the turbulent forces of the universe and to gain a better understanding of our place in the galaxy,†said Los Alamos’s Herb Funsten, part of the original research team responsible for development of one of IBEX’s cameras.
Caption:Â An artist's conception of the Interstellar Boundary Explorer (IBEX) spacecraft.
About Los Alamos National Laboratory (www.lanl.gov)
Los Alamos National Laboratory, a multidisciplinary research institution engaged in strategic science on behalf of national security, is operated by Los Alamos National Security, LLC, a team composed of Bechtel National, the University of California, The Babcock & Wilcox Company, and URS for the Department of Energy’s National Nuclear Security Administration.
Los Alamos enhances national security by ensuring the safety and reliability of the U.S. nuclear stockpile, developing technologies to reduce threats from weapons of mass destruction, and solving problems related to energy, environment, infrastructure, health, and global security concerns.
Los Alamos honors four for science leadership, research
Stars in hydrogen storage, carbon nanotube spectroscopy, space weather and weapons physics noted for 2011 achievements
LOS ALAMOS, NEW MEXICO, January 30, 2012—Achievements in scientific research and leadership are being honored at Los Alamos National Laboratory this week.
Laboratory Director Charles McMillan and the Laboratory’s Fellows organization have awarded the 2011 Fellows Prize for Leadership in Science or Engineering to scientists John Gordon of LANL’s Inorganic Isotope & Actinide Chemistry group and Geoffrey Reeves of the Lab’s Space Science & Applications group.
"This year’s Fellows Prize winners embody the excellence of the science that is so vital to completing our national security missions," McMillan said. "I congratulate each of the four winners and salute their creativity and innovation."
The 2011 Fellows Prize for Research goes to Stephen Doorn of the Center for Integrated Nanotechnologies and David Jablonski of the XTD Primary Physics group.
The following is a summary of the awardees' accomplishments.
John Gordon has led a team of chemists working on chemical energy that has achieved national and international recognition for the Los Alamos-led Center of Excellence for Chemical Hydrogen Storage. Gordon’s team solved a longstanding problem in the regeneration of ammonia borane from spent, dehydrogenated fuel materials.
Gordon also formed and is currently leading a team that focuses on the conversion of small-molecule carbohydrates into much higher energy transportation fuels and the related problem of generating non-petroleum based feedstocks.
Gordon has built an important Laboratory capability in chemical energy conversion and storage by recruiting and mentoring excellent young postdoctoral fellows and staff. In addition to his scientific leadership in chemistry, Gordon has served the Laboratory and the broader scientific community in a number of important capacities including a two-year assignment to the Department of Energy’s Office of Basic Energy Sciences and serving as leader of Inorganic, Isotope, and Actinide Chemistry group at LANL.
Geoffrey Reeves has been the prime architect and organizer of the Laboratory’s growing effort in magnetospheric physics, and he has been a leader in the development of space weather research as a key element of the Laboratory’s threat reduction mission. He recognized that such a capability could make major contributions not only to the Laboratory’s satellite nuclear test detection program but also to the national Space Weather Program and Department of Defense-sponsored national security applications such as Space Situational Awareness.
Over the past decade, Reeves has formed a team of highly capable scientists with the skills required to attack the multifaceted problem of modeling, understanding and predicting the radiation environment of Earth’s magnetosphere. His vision has evolved into the DREAM (Dynamic Radiation Environment Assimilative Model) concept to develop a model of the radiation hazards associated with a high-altitude nuclear explosion. Under Reeves’s guidance, the DREAM team has managed well to balance forefront basic space research with programmatic deliverables. The DREAM team is now recognized by the scientific community as a significant force in the worldwide effort to understand the space environment.
Fellows Prize for Research: Doorn and Jablonski
Stephen Doorn is an intellectual leader in carbon nanotube spectroscopy and is best known in the nanotube community for his groundbreaking advances in Raman spectroscopy of nanotubes, with many examples of “first-ever†types of experiments. He has distinguished himself with numerous scientific accomplishments in the area of spectroscopic studies of carbon nanomaterials, particularly single-walled carbon nanotubes.
Doorn has also developed important materials chemistry to help separate carbon nanotube mixtures and to integrate carbon nanotubes into composite materials. He has published 69 papers with more than 1,600 citations since 2001. Although the focus of Doorn’s contributions is the spectroscopy of carbon nanomaterials, he has made many significant contributions to other areas of nanoscience and nanotechnology. In particular, he has a substantial research portfolio and publication record in the area of plasmonic nanomaterials as surface-enhanced Raman scattering tags and substrates.
David Jablonski is recognized for his significant contribution to the 2010 Level-1 Energy Balance Milepost, resolving a 35-year problem in weapons physics that limited predictive capability. Jablonski performed a careful study of energy partition using Advanced Strategic Computing (ASC) and legacy codes; he isolated and highlighted the contributing factors to this problem and showed how higher fidelity in physical models and mesh resolution achievable with the ASC codes mitigated the problem
In the process of this five-year Milepost work, Jablonski made the ASC code more useful for the weapons research community, pioneering how to use it efficiently and testing various options, and formulated and coded some physical models himself. Jablonski's approach to using this code has become the standard for the weapons community at Los Alamos.
About Los Alamos National Laboratory (www.lanl.gov)
Los Alamos National Laboratory, a multidisciplinary research institution engaged in strategic science on behalf of national security, is operated by Los Alamos National Security, LLC, a team composed of Bechtel National, the University of California, The Babcock & Wilcox Company, and URS for the Department of Energy’s National Nuclear Security Administration.
Los Alamos enhances national security by ensuring the safety and reliability of the U.S. nuclear stockpile, developing technologies to reduce threats from weapons of mass destruction, and solving problems related to energy, environment, infrastructure, health, and global security concerns.
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Comments: 2
Thanks very much.