I have been taking Sam-e Complete for 13 days. I was selected to receive a free sample of this product on gather. The sample pack included 36 400 mg tablets of the Nature Made Sam-e Complete. The package says it is clinically proven for naturally restoring a healthy mood. This is a quote from the box. "What most people don't know is that an imbalance can be associated with low levels of ( S-adenosylmethionine) Sam-e, a naturally occurring molecule produced by your body." Things like aging and a poor diet can contribute to lower levels.
I have been taking it every morning at least 30 minutes before a meal. I haven't increased the 400 mg dosage yet, but you can increase it gradually if needed to determine what works best for you. This review is 5 days late, but I was waiting to give it enough time to work.
I have noticed that I feel less "moody". I had a phone conversation this morning that might have otherwise gotten a momentary rise out of me and it didn't. I joked with my husband that the person I talked to was "harshing my mellow", but they really didn't. I am defintely going to keep taking the Sam-e complete!