Patients who are having trouble sleeping often come in to my office asking about herbal supplements. One that has come to my attention recently is Ambrotose. The below article, written by Dr. Celeste Robb-Nicholson and first published in Harvard Women’s Health Watch, explains what this supplement is.
Q. What do you know about the health supplement Ambrotose? I looked it up on the Internet, where it’s described as an “advanced glyconutrient.”
A. The term “glyconutrient” sounds impressive, but it simply means sugar (glyco) that the body can use (nutrient). Ambrotose is a combination of eight sugars the body uses to make glycoproteins (proteins with sugar molecules attached). Proponents claim that Ambrotose has beneficial effects on conditions ranging from sleep, memory, and mental disorders to hypertension, asthma, and allergies. On the basis of limited research in cell cultures, they also say that it boosts the immune system. There’s no good evidence to back any of these claims.
Glycoproteins are important in communication between cells. Although they’re required for normal biological functioning, our bodies make all we need from the food we eat. Except for a few people with rare genetic conditions, there’s no evidence that humans are deficient in glycoproteins, and there are no controlled studies showing that “glyconutrients” can help treat or prevent any disorder.
These supplements are not rigorously tested for safety, but they’re probably fairly safe, apart from occasional allergic reactions, because the ingredients come mainly from food plants. The real danger is that they’ll be substituted for proven therapies. The American Cancer Society has issued a statement warning cancer patients against using glyconutrient supplements, supposedly to boost their immune systems, in lieu of medical treatment.
What have you heard about Ambrotose? If you have taken the supplement, let us know your experience.
Julie K. Silver, M.D., is an assistant professor in the Department of Physical Medicine and Rehabilitation at Harvard Medical School. She is also the Chief Editor of Books for Harvard Health Publications.
SleepNeed better sleep? Learn how to get it with Improving Sleep: A guide to a good night's rest. This special report from Harvard Medical School describes the factors that can disturb sleep, the latest in sleep research, and, most importantly, what you can do to get a good night's sleep. It also includes in-depth information on sleep disorders, including restless legs syndrome, narcolepsy, and sleep apnea.
Are you Living With Insomnia? Connect with others with similar health concerns and issues. Click here to join the group.
This content is not intended to substitute for personalized medical advice, diagnosis, or treatment from your healthcare provider. Read our full disclaimer.


Comments: 7
You must know that 5 of the eight [at least], essential sugars are in human breast milk, known to be best for babies' general well being extending for many years... so obviously in no way toxic.
Also when the sugars [specifically acemannan] were first discovered to have helpful effects, Stage 1 and 2 trials using cells, animals of many kinds,, then student volunteers were undertaken to find toxicity, and absolutley none was found. The FDA, to whom the results were submitted, said,basically, go away... not toxic, no LD50, not a drug, but a food.
Yes the body can make the various sugars essential to almost every cell function, but the conversions involve many enzyme steps, needing at any stage, particular co-factors, or vitamins, or minerals, to complete the process properly.
There are pathways to absorb the sugars in foods or as supplements accross the bowel wall, sometimes via the actions of "good" bacteria.
Taking glyconutrient supplements has been shown in many studies, and in personal experience of myself and many patients, to be very helpful for improbving well-being in many ways.
You should know how much less nutrient rich our various foods have become... which is why supplementation with glyconutrients, as well as vitamins, minerals are needed.
Rochelle MB BS DARCP/S [London]
“According to a six-year study at UC-Irvine on natural products and their effect on the immune system published in the Journal of the American Nutraceutical Association, the top four products were glyconutrients, phytochemicals, garlic, and aloe. All of these are extremely high in antioxidants.”
http://www.bluelight.com.cn/be-prepared-for-bio-terrorismhttp://
I won't go a day with out taking Advance Ambrotose. Neither will my wife and my 2 kids.
My family has been pharmaceutical free for 4 years. My staff also takes Glyconutrition and we have no sick days (Yes, they are available and offered, just not needed) and our employees are more productive. We cut our insurance premiums in half as we rarely visit the Doctor.
Steve Sears
ourhealth@alldayimage.com
www.alldayimage.com